Examined main and interactive effects of multiple social risk factors and preschool IQ and mental health on students' academic trajectories from first to twelfth grade. Found that high-risk students had lower grades and more absences from first to twelfth grade than low-risk students. Higher IQ and better mental health improved the grade point average (GPA) trajectories of low-risk children, but did not influence GPA trajectories of high-risk children. (Author/KB)