Background: This two-site pilot study examined the feasibility, acceptability and preliminary outcomes of "PODER Familiar," a culturally tailored intervention to promote the health and well-being of Latina family caregivers and their children with intellectual and developmental disabilities. Method: Using the Promotora de Salud model and mixed-methods design, we co-developed "PODER Familiar" with Latina caregivers of children with intellectual and developmental disabilities and community stakeholders. Thirty Latina caregivers and their children with disabilities were recruited to participate in the intervention, which included 10 individual sessions and 3 group sessions. Results: Twenty-six Latina caregivers completed all 10 individual sessions, with high intervention fidelity and satisfaction. Preliminary data showed improvements in psychosocial, behavioural, and health outcomes of Latina family caregivers and their children. Participants also highlighted cultural relevance, the value of promotoras, and positive impacts on family health behaviours. Conclusion: Preliminary findings suggest that "PODER Familiar" is a promising approach. Recommendations are included.