This study examines the determinants of academia-industry collaboration (AIC) in the context of Bariloche, Argentina, and provides valuable insights into collaboration dynamics in a developing economy. Using a quantitative research approach, data was collected through a survey administered to academic researchers in Bariloche. The survey included questions on researcher characteristics, organizational attributes, and disciplinary norms, which were then tested through eight hypotheses related to factors influencing AIC. Data analysis, including descriptive and inferential statistics, revealed significant relationships between independent variables (e.g., prior career experience, organizational affiliation, disciplinary norms) and researchers' involvement in AIC. The study's limitations, such as reliance on self-reported data and non-probabilistic sampling, are acknowledged. Nevertheless, the findings contribute to the understanding of AIC in Bariloche and have implications for promoting effective academia-industry partnerships. Future research should consider longitudinal studies and explore additional factors to inform evidence-based policies in developing economies.