Purpose: Public libraries play a pivotal role in supporting education and literacy. They provide numerous services, activities, collections and resources for education and leisure. Bibliotheca Alexandrina (BA) is an international renowned public library that provides numerous services for different users worldwide. E-learning is an emergent and promising method for teaching and learning different subjects such as the science, technology, engineering and mathematics (STEM). The e-learning educational system is quite novel in Africa and the Middle East; hence, this paper presents the whole concept to the reader. In addition, it demonstrates number of e-courses tackling different domains provided by different educational institutions, national and public libraries worldwide. Design/methodology/approach: In 2017, the BA inaugurated its e-learning services to cope with the new educational trend and to consolidate the lifelong learning concept in the community. The author showed special interest to the case of e-learning in the BA, as it is a regional public library. The main idea of this paper is to attract attention toward public libraries as a promising venue for e-learning implementation for general knowledge, library information sciences, soft skills, elementary and informal STEM education. The paper discusses in details e-learning and its characteristics. Findings: In addition, the paper compares traditional education (face-to-face) with e-learning education, mentions both their pros and cons and recommends blending the two educational methods as they complement each other. Furthermore, the author has selected a sample of different STEM e-courses (203 different e-courses). These e-courses were selected to assert the possibility of presenting STEM topics in the form of e-courses. Originality/value: This study would be one of the emergent research studies that connect e-learning to both STEM disciplines and public libraries. Additionally, this research highlights the importance of public libraries and all the services they provide. In the mean time, it shed light on the important and unique role of specialized librarians. Briefly, public libraries with all their resources, services and expert librarians could provide an exceptional e-learning experience to their community and be of great help to educational institutions and organizations.