Purpose: The purpose of this paper is to explore the trends of Cambodian government scholarship students' choice of academic major; the significant association between family socioeconomic status (SES) and Science, Technology, Engineering, and Mathematics (STEM) majors, and the patterns of STEM major choices across demographic and geographical characteristics. Design/methodology/approach: Descriptive analysis and cross-tabulation statistical tests were employed to analyze the data of 1,000 students drawn from the Ministry of Education, Youth and Sport scholarships database of 2018. The study employed a correlational study design. Findings: Findings revealed that the Cambodian government scholarship students were more inclined to major in social science than science and engineering-related fields. Findings also positioned that students' choice of STEM majors was significantly associated with family SES, gender and locality. Students from families with higher SES, male students and students from the provinces were more likely to choose STEM majors than their counterparts. Originality/value: These findings point to some practical considerations on how to maximize low SES students' enrollment in STEM majors at a higher education of Cambodia.