This qualitative case study examines the cultural adaptation of digital learning tools in Israeli higher education. We explored three questions: (1) How do lecturers experience and implement digital learning tools? (2) What unique challenges and opportunities arise in this cultural context? (3) What strategies do educators employ for culturally sensitive adaptation? Through semi-structured interviews with 15 lecturers, we identified four key themes: balancing traditional and digital pedagogies, cultivating cultural resonance, addressing integration challenges, and developing innovative strategies. These findings informed the Cultural-Adaptation Digital Learning Integration (CADLI) Framework, which extends existing models by centralizing cultural dimensions. Our study reveals that effective cultural adaptation involves 'cultural-technological co-evolution', fundamentally reimagining educational practices. This research contributes valuable insights for policymakers and practitioners navigating technological advancement and cultural preservation in higher education.