Extant research has explored practices and challenges for developing intercultural interactions on campus, but there is limited work on how cultural disdain has affected the development of intercultural interaction between domestic and international students. Drawing on interviews with 25 international students and 14 Chinese students in two Chinese universities, this study reveals that China's social history of intercultural encounters and internationalisation, together with people's individual intercultural experiences have fuelled Chinese students' perceptions of the superiority of English language and Anglo-Saxon culture. While Chinese students prioritise communication with peers who are English native speakers, they tend to develop deeper intercultural friendships with students from non-Anglo-Saxon countries. This study uses the theory of cultural disdain to interpret the complex dynamics of intercultural interaction on campuses. It argues that Chinese universities need to increase cultural diversity and foster equality between different cultural groups in order to promote fruitful intercultural interactions for all students.