Transforming curriculum by implementing Problem-Based Learning (PBL) in the college-level classroom helps students internalize the concepts of a course, improve their critical and reflective thinking skills, learn to problem-solve using questioning, and ultimately construct a better understanding of course concepts in a personally relevant way. This article introduces a process for implementing PBL in a college-level course. Each of the four main ideas in PBL, motivation, collaboration, reflection, and facilitation, are addressed with a particular focus on the role of the educator in designing and implementing PBL in the classroom. An example of how the process works in a specific college-level course is provided with explanations of the thinking that went into each of the steps in the process and the outcomes of the implementation, including examples of student assignments and the challenges and benefits of the implementation.