This research aimed to determine students' opinions on technology-supported drama activities applied in teaching the subject of the central nervous system in the biology course. The research used a case study design, a qualitative research method. The study was conducted with 25 students studying biology at a state university. An appropriate sampling method was used to determine the study group. Within the scope of the research, a semi-structured interview form was used to determine students' opinions about technology-supported drama method applications. This form allowed students to express their experiences in depth. The research results indicated that the students had a generally positive perspective on the technology-supported drama method used in the biology course. Since technology-supported creative drama activities provide students with a learning environment that they enjoy, this method can be recommended to increase students' interest in lessons and ensure permanent learning of content.