Suicide rates among Black youth have risen faster than any other racial/ethnic group in the past two decades. Black youth residing in rural areas are subject to systemic challenges such as minimal access to mental healthcare providers, generational poverty and oppressive social structures that lead to racial discrimination. Racial discrimination places rural Black youth at increased risk for anxiety, depression, and suicide. Protective factors have been found to mitigate the negative impact of racial discrimination on mental health, but there is limited research covering suicidality and Black youth. This scoping review explores what is known about the role of protective factors in moderating the association between racism/discrimination and suicide risk among Black youth in the United States. Findings were mixed regarding the influence of protective factors in moderating the effects of racial discrimination on suicide risk and more exploration among Black youth in impoverished rural areas is warranted.