The emergence of a global emergency, COVID-19, forced social work programs to shift to virtual teaching, disrupting students' learning abruptly. Social work students reported negative impacts from the pandemic on academic functioning as well as financial and emotional wellbeing. This study examines the relationships between demographic predictors (age, race, type of social work program, caregiver status, first-generation college student, household size) and challenges (emotional, academic/professional, financial, technological) social work students experienced during the pandemic. Participants included 332 BSW and MSW students from an urban university. Binomial regressions were conducted to determine the significance between student demographics and types of challenges. A Poisson regression was performed to determine the significance between student demographics and the total number of challenges. Students living in larger households, students with greater caregiver demands, BSW students, and students of color reported a greater number of challenges related to juggling school with caregiver demands, job searching, managing finances, food and housing, coping with grief and loss, and feeling disconnected with school (ps <0.05). These findings contribute to the emerging body of literature on the impact of COVID-19 by informing ways social work schools can better address students' educational, professional, financial, and emotional wellbeing during times of worldwide crisis.