The aim of the study is to adapt the "Maker-Based Technological Pedagogical Content Knowledge" scale developed by Ku et al. (2021) for pre-service science teachers into Turkish. The study group for the research consists of 188 pre-service science teachers studying at the Department of Science Education at three state universities in Istanbul. This study was carried out using an exploratory sequential design, one of the mixed method typologies. As a result of confirmatory factor analyses, it was seen that the scale, which was adapted into Turkish, consisted of 7 sub-dimensions and 27 items, as in the original. These 7 sub-dimensions consist of Content Knowledge, Pedagogical Knowledge, Technological Knowledge, Pedagogical Content Knowledge, Technological Content Knowledge, Technological Pedagogical Knowledge, and Technological Pedagogical Content Knowledge. The Cronbach Alpha Reliability Coefficient of the scale is 0.948. The validity of the scale was confirmed via confirmatory factor analysis. As a result of confirmatory factor analyses, it was seen that the scale, which was adapted into Turkish, consisted of 7 sub-dimensions and 27 items, as in the original (X[superscript 2] =718.83, df=303, p= 0.00), and the x[superscript 2]/df value for model fit was found to be 2.37, RMSEA: 0.080, RMR: 0.0498, SRMR: 0.0759, IFI: 0.966, NFI: 0.942, NNFI: 0.960 and CFI: 0.965. Because all fit values are in acceptable levels, the scale is usable and valid. The results of the study show that the adapted scale is a valid and reliable scale that can be used to measure the Maker-Based Technological Pedagogical Content Knowledge of pre-service science teachers.