Engaging students in active learning has proved to transform reflexive knowledge into true learning of material in medical education. Histology is one subject area that consistently presents as a challenge for medical and undergraduate students. The large amount of complex information needed to completely understand and interpret histological images is something that is many medical students do not fully grasp in the pre-clinical stages. Pedagogical studies that use physical objects and hands on learning have been shown to motivate and encourage students to self-learn such complex topics. This application of using physical objects and hands on learning, however, is not the easiest to translate to the cellular level. The Histo-Kitchen was designed to help students manage the vast amount of information and acquire knowledge in a meaningful and creative way. By incorporating food items into an active learning session, students were able to stretch their imagination and find representative items for common histological specimen representations. Based on post-session discussions, students found the activity to be beneficial to their learning and greatly enjoyed participating in the activity, often citing it as the most fun they have had learning histology. By providing students with opportunities to interact with complex material in creative and novel ways, students are able to learn in an environment that can be both engaging and enjoyable.