Although each person faces their own share of challenges, it is their individual perception and responses to these difficulties that determine how they are affected by them. In this paper we investigate the association between gratitude and human prosperity including the underlying mechanism that helps people thrive during trying circumstances. We survey the literature, examining how gratitude enables people to prosper amidst adversity and employ a narrative style to present these unique characteristics. This review suggests that gratitude enhances coping abilities, such as meaning-focused coping and positive reframing, which foster positive emotions and augment personal resources like resilience, perseverance, and social bonds. These elements, in turn, may possibly explain the association between gratitude and human prosperity during dire circumstances.