Higher education in the Gaza Strip has been subjected to four wars and over a decade of blockade. University staff and students have been killed whilst campus infrastructure has been attacked, rebuilt, and destroyed again. This paper examines opportunities for, and limits to, protecting higher education from attack in Gaza. It presents a framework for categorising protection measures and empirically explores the effectiveness of measures to protect higher education from attack in Gaza since 2007. It finds that whilst Gaza's academics and students generally express hopelessness at protection under blockade and asymmetric warfare, there are promising potential avenues for protection.