Innovations in teaching and learning led to HyFlex, a new type of hybrid teaching modality that incorporates in-person learning options along with online learning (Beatty, 2019). In May and June 2022, faculty at a regional comprehensive university were invited to participate in in-depth interviews or open-ended surveys regarding their experiences teaching HyFlex. Based on six in-depth interviews and six open-ended survey responses, this study's three main findings related to themes of interaction, technological challenges, and increased workload. We conclude that teaching innovations like HyFlex can both enrich a faculty member's sense of self-efficacy and contribute to additional stressors of work responsibilities (Leijon & Lundgren, 2019; McNaughton et al., 2014; Malczyk, 2019). These challenges will need to be addressed by institutions and faculty.