The paper examines the role of Information and Communication Technology (ICT) in special education in Ghana. Taking the relevant literature as the guiding principle, the paper addresses the opportunities, barriers, and challenges posed by the integration of assistive technologies devices in schools for the blind and visually impaired in the teaching and learning process. The paper shows that inadequacies of teachers' knowledge and skills in assistive technologies coupled with lack of these technologies are some of the greatest hindrances to effective teaching in the schools for the blind in Ghana. Educators and policymakers acknowledge Evidence-Based Teaching (EBT) as one of the most effective strategies for teaching the blind and the visually impaired. The paper highlights that effective integration of assistive technologies into schools will help bridge the digital gap between the blind and the sighted in Ghana.