This article uses the question "Can government and businesses mandate the COVID-19 vaccine?" as a starting point for an interdisciplinary lesson appropriate for a variety of business law classes. This lesson includes several important overlapping learning goals: (1) It expands students' ability to analyze how the complexity associated with the legal regulation of business in the United States applies to real-world business dilemmas; (2) improves students' ability to examine business dilemmas from competing ethical perspectives and distinguish between law and ethics; (3) develop students' ability to critically assess how behavioral economics can further a business's goals; and (4) develops students' ability to integrate knowledge across disciplines including law, ethics, and behavioral economics. This lesson is appropriate for a variety of classes, and Debbie Kaminer has used it in courses she teaches on both the Legal and Ethical Environment of Business and Employment Law at both the undergraduate and graduate levels.