This paper presents an application of the Kalman filter in signal processing in instrumentation systems when the conditions of the environment generate a large amount of interference for the acquisition of signals from measurement systems. The unwanted interferences make important use of the instrumentation system resources and do not represent useful information under any aspect. A simulation is presented using the Matlab tool, which remarkably facilitates the information processing so that the corresponding actions are taken according to the information obtained, taking advantage of the current resources offered by the embedded systems and the required measurements are obtained with enough accuracy.