In Africa, inclusive education has been demonstrated at the primary level and has been improving at the secondary level. However, inclusion is yet to be fully realized in employment and entrepreneurship. The few persons with special needs who have experienced inclusion have demonstrated success, yet some communities are not ready to give them opportunity and support their needs. The cases of Siminyo, Akinyi, and Bulimi are exceptional and serve as role models to persons with disabilities and society. The purpose of this study was to establish the impact of inclusion of persons with disabilities in mainstream society in Kenya in terms of employment and entrepreneurship. The objective was to demonstrate how inclusion practices enhance acceptance and improve the lifestyle of persons with disabilities. A case study methodology was implemented with people with three different types of disabilities. The study identified the importance of inclusion practices in society. The results established that if persons with disabilities are integrated early enough in life, they can live a fulfilling life in their communities without depending on other people.