Objective: This study examined relationship mindfulness and negative emotional symptoms as serial mediators between relationship satisfaction and sleep problems. Participants: Participants were 242 college students currently in a romantic relationship recruited from a large southeastern university. Methods: Participants completed self-report measures of relationship satisfaction, relationship mindfulness, negative emotional symptoms and sleep disturbances. Serial mediation analyses were conducted, covarying age and attachment orientations. Results: Students who reported higher relationship satisfaction experienced lower sleep problems. Helping explain this association a significant serial mediation model was supported by which relationship mindfulness and subsequent negative emotional symptoms mediated relationship satisfaction and sleep problems. Conclusions: The degree to which a person is more mindful during interactions with a romantic partner appears to play a key role in how relationship satisfaction and negative emotional symptoms are linked to sleep problems.