Biochemistry is believed to be a difficult subject to understand for most life science and medical students. This article explains an experience with a flowchart-based teaching approach that is applicable to different kinds of biochemistry courses (basic, medical, and clinical) for undergraduate and postgraduate students. After preparing the flowcharts, they were given to the students at the beginning of the semester, and the flowchart-based teaching was performed for a whole semester. At the end of the semester, they were asked about the effectiveness and facilitation of learning using flowchart-based teaching. This survey was performed for several semesters. Approximately, 95% stated that it facilitates learning and understanding.