ERIC Number: EJ1349364
Record Type: Journal
Publication Date: 2022
Pages: 3
Abstractor: As Provided
ISBN: N/A
ISSN: ISSN-1470-8175
EISSN: EISSN-1539-3429
Available Date: N/A
Using Large Databases to Study Cancer Genomics in an Undergraduate Classroom
Melloy, Patricia G.; Chiswell, Brian; Peterson, Celeste
Biochemistry and Molecular Biology Education, v50 n5 p460-462 Sep-Oct 2022
Cancer databases collect original cancer studies and patient clinical information into one site that allows for global analysis. While many courses focus on cancer, few utilize these powerful cancer databases. Our goal was to create a lab experience in which students could explore original cancer study databases, looking at the expression and incidence of driver mutations of cancer. First, the students focus on a specific patient including demographic data and type of cancer. Then the students analyze mRNA expression levels associated with mutations of the gene, determining if it is a tumor suppressor or oncogene. Students also learn which mutations are actionable and how they affect survival. In summary, this module allows students to analyze global trends in driver mutations in cancers and dive into specific patient features.
Descriptors: Cancer, Databases, Patients, Incidence, Correlation, Undergraduate Students, Teaching Methods, Laboratory Experiments, Science Education, Genetics, Trend Analysis
Wiley. Available from: John Wiley & Sons, Inc. 111 River Street, Hoboken, NJ 07030. Tel: 800-835-6770; e-mail: cs-journals@wiley.com; Web site: https://www-wiley-com.bibliotheek.ehb.be/en-us
Publication Type: Journal Articles; Reports - Research
Education Level: Higher Education; Postsecondary Education
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A
Grant or Contract Numbers: N/A
Author Affiliations: N/A