Work-integrated learning (WIL) has become an essential component of many university curricula. Recent global disruptions have challenged traditional models of WIL, particularly industry-based student placements, leading to growing calls for new, sustainable models of WIL. Aligned with this call and the increased emphasis on learning across disciplines, interdisciplinary project-based WIL provides an alternative to student placements that is both student and industry centered. This study reports on the outcomes of pilots of this model of WIL across four Australian universities. A cohort of 38 students, faculty and industry staff who participated in the pilots were interviewed. The key challenges and enablers of interdisciplinary project-based WIL are identified along with recommendations for implementation.