The purpose of this study was to examine the relationship between curiosity, gratitude, and life satisfaction in undergraduate college students. It was hypothesized that there would be a significant relationship between gratitude, curiosity, and satisfaction with life. College students from a southeastern college were recruited via email, in-class announcements, and throughout campus via QR codes to participate in the study. A total of 300 undergraduate students consented to participate in the research study and 231 completed the surveys. Participants completed surveys assessing curiosity, gratitude, and satisfaction with life. Data was analyzed using descriptive statistics, Pearson's r correlations, and separate one-way ANOVAs to determine group differences in gratitude, curiosity, and satisfaction with life. Hedge's g effect sizes were calculated as well. Gratitude was positively related to curiosity (r = 0.20), and satisfaction with life (r = 0.36). Furthermore, women exhibited greater gratitude as well as satisfaction with life when compared to men, [F(2,230) = 14.40, p < 0.001]. These results are consistent with the hypotheses and will be discussed in regard to previous research and future application.