The aim of the study is to develop an analytical framework to study the effect of Information and Communication Technology (ICT) education on humanistic innovative potential. The study recruited 150 school age children from three secondary schools and 100 university students from two universities in Russia. Each respondent's humanistic potential was measured using the Pomitkin's Spiritual Potential of a Personality Inventory. The proposed framework consists of several components: a motivational component, a content component, an activity component, a value component, and an imitational component. The results of the study show that the proposed framework allows improving the spiritual potential of learners. The percentage of learners with low spiritual potential dropped 24% (among school students) and 12% (among university students). The proposed framework is expected to optimize the teaching/learning process with ICTs and direct the student's learning toward enhancing the humanistic innovative potential.