At both the undergraduate and graduate level, an increasing number of students are completing their coursework online or in hybrid formats. As online learning grows and evolves, and new teaching tools emerge, it is useful to review approaches for effective teaching in this modality. This paper focuses, in particular, on proven tools in online teaching that can be employed in courses with a strong quantitative analysis component, such as political methodology and political economy courses. We first highlight critical areas of focus, including text analysis, survey research, artificial intelligence and the communication of results. We then discuss methods and technologies that can be used to teach in these areas, such as social media and news APIs, online labor markets, online meeting spaces and simulation exercises. The final section explores methods for providing meaningful feedback on the types of assignments commonly used when teaching quantitative methods. This review of key areas of focus, learning tools, and methods for providing feedback in online quantitative courses will arm faculty with an understanding of how to develop and deliver courses that encourage participation and impart a deep knowledge of the subject at hand.