Research and practice emphasize the importance of family involvement in early intervention for children with autism spectrum disorder (ASD). However, in order to address the unique and diverse challenges of families, support and resources may need to be prescribed on a case-by-case basis. This article suggests ways early intervention programs can assess parent stress, self-efficacy and disability specific knowledge at time of ASD diagnosis to inform family centered intervention programs with attention to individualized support for children with ASD and their families. A variety of assessment tools are provided with rationale for their use of results to inform program intervention and service plans for families of young children with ASD.