Increasingly evidence suggests that the self-reported health status (SRH) of 2nd generation immigrant youth (native-born youth with at least one parent who was born abroad) may be lower than non-immigrant youth. This cross-sectional study compared the SRH of 2nd generation immigrant to non-immigrant youth (n = 291), accounting for confounders including a clinical measure (i.e., body mass index), internal resources (i.e., diet, exercise, smoking), and external resources (i.e., socioeconomic status, family social support). Regressions showed SRH was associated with socioeconomic status (p < 0.05), family social support (p < 0.05) and exercise (p < 0.05) but not immigrant status. Yet, bivariate analyses, showed that among youth, 2nd generation immigrants had poorer diets (p < 0.01), were smokers (p < 0.0001), had lower socioeconomic status (p < 0.05) and less family social support (p < 0.05). Thus, although SRH did not differ by immigration status among youth, the differences in internal and external resources by immigrant status may lead to health differences in the future.