The purpose of the study is to compare the effectiveness of mind mapping in the traditional and mobile learning environments. The study explores whether traditional offline learning activities, including mind mapping, can be improved when using online learning platforms. Mind mapping was used in the entrepreneurship course on launching startups to brainstorm and present a business idea. The study was conducted in 2020 and involved 271 undergraduate medical students studying at Sofia University, Bulgaria and Sechenov First Moscow State Medicinal University, Russia. The results of the experiment showed that students who studied in the traditional offline environment performed better compared to those who used their mobile devices. The general concept of mobile learning has been considered. Thus, the approach enables students to choose the most suitable devices for solving various problems. In order to increase the effectiveness of mind mapping in the educational process, tasks can be performed offline and online. The practical significance of the results obtained lies in the fact that they allow the selection of the most effective offline and mobile learning technologies to make mind maps.