The study evaluated safe sex attitudes and intentions from a comprehensive, peer-led sexual health program for teenage students enrolled in three rural colleges in Mississippi. The methods consisted of pretest and posttest survey items regarding attitudes and intentions toward safe sex from 149 participants and a peer educator focus group on curriculum delivery and participation. Intentions and motivations for contraception and sexual risk awareness significantly improved at posttest for all participants. The focus group suggested that peer-led approaches are critical for engaging students, fostering participation, and addressing students' sexual health needs in culturally sensitive ways.