Advances in information technologies present opportunities for novel approaches, methods, and tools for new or improved education and training practices. Furthermore, these technologies are enabling a shift in the education paradigm. Based on an investigation of a wide range of information technologies supporting smart education, we developed a Smart Education Framework. The framework conceptually structures the information technologies in a layered architecture. We also developed a smart education design approach based on the framework. Furthermore, we show how to use the framework and design approach to develop a specific course or lecture design. To validate the smart education framework, we examined smart education systems reported in the literature. To identify smart education systems, we conducted a systematic literature search. The literature search results show that the smart education framework has the ability to describe smart education systems. This study contributes to the current literature with a smart education framework. The smart education framework will guide future smart education system designs.