This article explores efforts to stimulate significant conversations through a Scholarship of Teaching and Learning (SoTL) Community of Practice (CoP) amongst a diverse group of professors and professional staff in a College of Applied Arts and Technology in Ontario, Canada. Participants share their reflections on the formation of significant networks and the start of significant conversations through the founding of a SoTL CoP. These reflections suggest that conversations fostered were shaped by various trusted and trusting individuals within a significant network. This trust assumes different forms and is central to significant networks and significant conversations.