This article addresses major lacunae in higher education from the standpoint of Anthropocenic survival. "Wicked problems" transcend national, cultural and disciplinary boundaries. Eco-survival, international migration, destabilized global markets, shifts in the balance of strategic power, population pressures, cultural imperialism, post-secular quests for meaning-in-life, ambivalence of bio-scientific progress, to name a selection, are "global." The case is put that features of a "postmodern" orientation to the academic curriculum--transdisciplinarity, transnationalism, wicked problem engagement--are better equipped to meet the "fuzzy" knowledge interests of tomorrow's world than traditional mono-disciplinary curricula. However, both subject-based and transdisciplinary approaches can coexist with profit in the education of tomorrow's global citizens. A paradigm shift in how we educate for survival is proposed here.