This study analyzed design and technological issues encountered by online course instructors as they taught 120 online courses while working with a designated instructional designer. Having developed the courses and having had them approved in compliance with a set, standardized rubric, implementation of the 120 courses brought out issues that required the assistance of an instructional designer to be resolved. The study identified and analyzed specific issues that cut across most courses. The study presents implications to faculty, instructional designers and administrators.