Relatively little is known about preschool teachers' read-aloud techniques with informational picture books. The purpose of this investigation was to identify similarities and differences between preschool teachers' read-aloud techniques with fictional stories, which are commonly read in preschool, and informational texts. Instrumental case study and purposive sampling were employed to investigate the reading techniques of two White female teachers in one preschool classroom as they read in small groups with children two-and-a-half to five years old. In terms of similarities across genres, teachers made personal connections, prompted children to interpret pictures, used multimodal instruction, and differentiated instruction. In terms of key differences, when reading fictional stories, teachers scaffolded children's inferences and predictions, whereas for informational texts, teachers described academic vocabulary and content and focused on informational text features. Preschool teachers might expect to use a core set of reading techniques across texts and also differentiate according to the type of picture book.