Transiting from a home country to a host country in pursuit of higher studies involves various psychological and sociocultural challenges. Accordingly, this phenomenological qualitative study explores the challenges faced by six Indian international graduate students in a US university. The study further integrates an interdisciplinary approach by including participants from different disciplines to generate an understanding of their collective experiences. The data analysis generated five themes related to the challenges encountered: (1) living away from family and friends; (2) difficulty in expressing; (3) multitasking; (4) difficulty in fitting in; and (5) lack of positive attitude. Findings have implications for US universities. Higher educational institutions can play an essential role in addressing the challenges to facilitate a positive academic experience for international students. [Note: The page range (259-273) shown on the PDF is incorrect. The correct page range for this article is p249-263.]