The present study aimed to evaluate whether children with autism spectrum disorder (ASD) were able to initiate requests for assistance by applying computer technology to the specific instructional procedure, which included behaviour chain interruption, time delay, prompting, and differential reinforcement. New software was developed in this study so that the instructional procedure could be conducted automatically by a computer device. A multiple baseline across participants design was adopted in this study, including one baseline phase and two intervention phases. Results show that the number of spontaneous requests made by three participants increased gradually. The findings demonstrate the feasibility of combining computer technology with the specific instructional procedure for teaching the participants to take the initiative to request assistance.