Feeling of loneliness is a matter that is commonly encountered among adolescents and young adults and should be taken into consideration. This study was conducted for the purpose of determining whether or not there was a correlation between the feeling of loneliness and burnout levels in university students. The purpose of the study is to determine whether or not the feeling of loneliness of university students affects their burnout levels. The sample group of the study consisted of 376 students receiving education in Harran University Vocational School of Healthcare Services. The data were collected using a questionnaire between 01-31 May 2019. UCLA Loneliness Scale and Maslach Burnout Inventory -- Student Form (MBI-SF) were applied to the study group. The data was analyzed using descriptive statistics and linear regression analysis (ANOVA) in the SPSS 20.0. The acquired results show that the scales used in the study has a higher reliability. Similarly, the results of the linear regression analysis ANOVA show that the feeling of loneliness has a significant effect on burnout. In the results of the linear regression analysis ANOVA, it is found out that the feeling of loneliness has a significant effect on the sub-dimensions of burnout. With regard to the standard regression coefficient, it is expected that 1-unit increase in the feeling of loneliness variable causes 0.279-unit increase in the perception of exhaustion variable. The higher the loneliness levels of students are the more the levels of exhaustion increase.