Communication is a complex phenomenon. How people interpret information to make decisions relies on an infinite amount of data that is different for every individual based on experience, education, socioeconomics, and belief systems. The complexity is compounded with subjects such as vaccinations, when patients must make decisions that impact their lives and that of their family. Evidence based information regarding vaccinations is readily available from government institutions and international health agencies. An example is the World Health Organization (WHO). With the advancements in technology, the world also has access to misinformation, including opinions from anyone who wants to share, especially through social media platforms. All these complexities contribute to challenges nurses have as they try to educate the public on the importance of vaccinations and how they protect individuals and communities. Particularly, for the vaccine hesitant community, nurses must employ careful measures to ensure that the information conveyed is received in a manner that educates their patients to make informed decisions.