Mobile phones can be functionalized in the process of learning using cellular devices and computing systems. The present study aims to (1) develop mobile learning applications and (2) find out student responses in the learning process using m-learning. This research used the 4D model (defining, designing, developing, and disseminating) written by Thiagarajan. Validation used a questionnaire to collect data, while effectiveness was revealed through student responses that took part in m-learning. The results showed (1) the application used in e-learning learning was very valid (> 85%), and (2) research subjects (two classes) provided very positive feedback (> 85%). It means that the mobile learning application developed is feasible to use because it has high validity and is able to increase students' positive responses. This study reveals that mobile learning applications can have a positive impact on student learning outcomes in the future.