The distance teaching of organic chemistry to first-year undergraduate students during lockdown represents a challenge for both students and teachers. To face this challenge, a method combining synchronous and asynchronous teaching was presented in this paper. The asynchronous part of the teaching was achieved through the broadcast of videos on the social network Facebook in order to allow each student to progress at his or her own pace. The synchronous part of the teaching was carried out thanks to the Discord platform in order to answer students' questions live (written and oral) as well as to keep a social link with them. The videos have been recorded at home with a minimum amount of material, and the equipment is reported. To assess the efficiency of this alternative teaching compared to distance real-time teaching during disruption, a questionnaire completed by students was used and discussed.