Previous studies regarding the effect of experiencing anger on creative performance have shown controversial findings. Some studies have reported that anger hampers creative performance, whereas others have shown that anger promotes cognitive motivation and improves creative performance. Anger is associated with hostility, threats, and conflict, states that are congruent with low agreeableness. In contrast, anger is incompatible with an agreeable individual's preference for harmony and peace. Experiencing this negative activating emotion should be demanding and stressful to them and thereby hamper creative task engagement. Accordingly, we conducted an experimental study to examine whether agreeableness moderated the association between anger and creative performance. A total of 128 undergraduates were randomly assigned to receive either induced anger or a neutral emotion and then completed a creativity task. We found that participants with lower levels of agreeableness showed better fluency, flexibility, and originality in creativity in the anger relative to the neutral-emotion condition, whereas participants with higher levels of agreeableness showed better creative performance in the neutral emotion relative to the anger condition. The present findings not only provide a viable account for integrating inconsistent findings regarding the facilitating effect of anger on creativity but also contribute to contingent strategies for promoting creative performance.