Many children as young as 7 years old journey across Central America to the USA, facing danger and uncertainty that influence their later physical and emotional development and socialization. This paper synthesizes the literature on the experiences of unaccompanied immigrant children from Latin America traveling to the USA, how the trauma of immigration can manifest in their development, and offers evidence-informed strategies that mental health service providers in the schools can implement. Results show that the initial negative events that promote immigration along with traumatic experiences during their migration journey suggest that child immigrants may be at a higher risk to experience acculturation-based problems, discrimination-based problems, and trauma-based difficulties. School psychologists are at the frontline of this crisis and need adequate resources and tools to respond to the needs of a segment of the school population that is increasingly at risk for serious mental health and poor socio-emotional outcomes. More research in this area is needed, especially as it applies to a school setting. Implications for interventions are discussed.