Science learning video integrated with local potentials was developed and tested to improve students' science process skills (SPS) and concept mastery. The learning video was developed for the topic of micro-hydro power (MHP) plant. This study was aimed to determine the effectiveness of the video integrated with the local potential of MHP plant in science learning. A quasi-experimental nonequivalent control group design was used. The population was first-year students of State Junior High School in Bantul Yogyakarta. The cluster random sampling was used to determine the sample. The aspects of SPS measured were observing and communicating, while the aspects of concept mastery measured were memorizing, understanding, and applying. The data of students' SPS and concept mastery were analyzed using multivariate test. The findings revealed that the use of video integrated with local potential of MHP plant was effective to improve students' SPS and concept mastery. This was statistically supported by the average normalized gain for the experimental group (medium category), which was higher than the control group (low category).