Text comprehension comprises processes that work interactively to create a situation model of a text. Three hundred and one students from 12 Estonian schools were assessed to examine the relations between vocabulary and different text comprehension levels and to detect students' individual profiles in these skills. Both variable- and person-oriented approaches were used to analyse overall patterns in the data as well as to make inferences regarding students' individual differences. Vocabulary was found to have the strongest influence on inferential and literal comprehension, whereas evaluative comprehension was slightly less related to vocabulary. Person-oriented approaches revealed different patterns in students' vocabulary and comprehension skills. Individual differences in vocabulary and comprehension levels emphasise the need to assess students' comprehension with multidimensional tests aimed at determining the shortcomings in comprehension components and tracking students' developmental changes.