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ERIC Number: EJ1243310
Record Type: Journal
Publication Date: 2020-Feb
Pages: 12
Abstractor: As Provided
ISBN: N/A
ISSN: ISSN-0021-9584
EISSN: N/A
Available Date: N/A
Make a Molecule: A Synthetic Organic and Medicinal Chemistry Workshop Program for High School Students
Stepek, Iain A.; Hofmann, Raphael; Nichols, Paula L.; Aschwanden, Andrea; Eckard, Christophe; Aschwanden, Patrick; Bode, Jeffrey W.
Journal of Chemical Education, v97 n2 p402-413 Feb 2020
Despite the importance of organic chemistry to human health and quality of life, very few outreach programs have been successful in communicating this message. This contributes to negative public perceptions of organic chemistry and obscures the enormous advances in quality of life engendered by organic synthesis. New chemical outreach programs that provide insight and hands-on experience of small molecule chemistry are vital to improving public engagement with the science. Make a Molecule is an organic chemistry workshop program that provides high school students with the opportunity to synthesize and biologically assess short peptides in a safe and easy manner, allowing them to experience the thrill of making and testing new bioactive molecules in a classroom environment. This manuscript details the development of the Make a Molecule project from its origins in our "synthetic fermentation" chemistry to its initial application in high schools. Scientific protocols were optimized to suit a classroom setting with the help of high school students. An accompanying website was constructed to serve as an experimental guide, aid with the workshop execution, and provide an educational resource for students and teachers. With everything in hand, the first Make a Molecule workshops were conducted in a local high school in Zurich, Switzerland, during which students were able to successfully synthesize and test novel bioactive molecules.
Division of Chemical Education, Inc. and ACS Publications Division of the American Chemical Society. 1155 Sixteenth Street NW, Washington, DC 20036. Tel: 800-227-5558; Tel: 202-872-4600; e-mail: eic@jce.acs.org; Web site: http://pubs.acs.org/jchemeduc
Publication Type: Journal Articles; Reports - Descriptive
Education Level: Secondary Education; High Schools
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A
Identifiers - Location: Switzerland
Grant or Contract Numbers: N/A
Author Affiliations: N/A