The Individuals with Disabilities Education Act (2004) and the Every Student Succeeds Act (2015) both require that educators utilize instructional practices based on evidence in the literature when providing special education and related services to students with disabilities. This article provides a description of a special type of literature review, the "meta-analysis," that may be of substantial assistance to educators. The essential characteristics of a meta-analysis are described as well as how they are performed, where to find them, and how to interpret their findings. A concluding comment on the relevance of meta-analysis to the implementation of evidence-based practices is presented.