Business schools strive to improve students' analytical skills by incorporating advanced business application software courses into their curricula. This study examined how business school students perceived the ease of using the software and the usefulness of using the software in learning. The study also explored whether and how students' perceived ease of use and usefulness of the software affected their attitude towards the use of business software and their intention to use the software. Data were collected from 159 Chinese business school students in a higher education institution in Macao. Results showed students generally agreed the software was easy to learn and use, and they agreed the software was useful. The results of structural equation modeling showed that perceived ease of use was directly and indirectly related to attitude towards the use of business software through its effect on perceived usefulness, whereas attitude towards the use of business software strongly affected the intention to use the software.