The aim of this study is to investigate the effectiveness of an educational program in improving the level of knowledge of parents about natural growth indicators in the development of children and determining the indicators which delay development in children from birth to three years old. The sample of the study consisted of 60 volunteers who were randomly and equally assigned to control and experimental groups. The educational program consists of 15 sessions; each session's duration is two hours. The results of the study showed that the level of parents' knowledge of natural growth indicators for children from birth to three years is low. There were differences on the level of knowledge of parents about developmental delay indicators due to the educational program. The study recommended the need for further studies on the importance of raising the level of knowledge of parents about development risk indicators of natural growth of children.